We often get asked by readers is S. boulardii is safe to consume for people with IBD and IBS and is it actually beneficial?
My answer up till now has been: When I tested it on myself – over 25 years ago – my body didn’t like it very much. And then I had a discussion with the then-president of the BC Naturopathic Association and he told me that while it might be okay in short-term doses, he did not recommend anyone take it long-term, as it is a yeast.
But now, we have additional hard-science evidence (from the Journal of Clinical Microbiology) that when you purchase Saccharomyces boulardii, that may not actually be what you’re ingesting.
Researchers purchased 3 different S. boulardii products commercially available in France and Italy. So this would be like you going to your local health store, or online, and buying an S. boulardii supplement.
Unfortunately, when they tried to test the products:
“…the commercial strains of S. boulardii available to us cannot be genotypically distinguished from S. cerevisiae.”
And what is Saccharomyces cerevisiae? It is another species of yeast that can be virulent (cause infection/harm) or avirulent (benign), depending on the strain.
What the researchers discovered from these retail supplements is:
“The results of the present study show that these S. boulardii strains are asporogenous strains of the species S. cerevisiae, not representatives of a distinct and separate species, and possess moderate virulence in murine models of systemic infection. Therefore, caution should be advised in the clinical use of these strains in immunocompromised patients…”
So there you go. This is similar to what can happen with digestive enzymes; most of them contain traces of the aspergillus spores they were cultured on. So when you’re assessing which supplement is actually going to benefit you, you must look at the manufacturer of the supplement – how are they producing it, what is their raw materials testing procedure, what is their finished product testing protocol?
These are some of the ‘insider info’ things Natasha Trenev (founder of Natren therapeutic probiotics) and I have been discussing in-depth in our Healthy Gut Bugs podcast/video series. Next week, we’re talking about Kombucha and Saccharomyces Boulardii – so make sure you’re subscribed to the blog and stay tuned…
Florastor contains a biocidex strain that has been studied and is in the scientific literature.
This article is misleading because there are studies of the biocidex strain of S Boulardii that are mentioned in the medical literature and available commercially such as Florastor and Penterol Forte among others. This really does a disservice to your readers. I would recommend checking PubMed for information on the biocidex strain which has been studied rather than using generic S Boulardii products.
What is the best natural healing for Colitis people with Saccharomyces cerevisiae units in >40.
Any natural drops like Oregano, Grapefruit seed extract?
Hi Ram – this is a question best posed for your doctor, however, it may be beneficial to implement an anti-pathogen (such as oregano oil, which is most powerful in Jini’s opinion) and re-populate the gut flora with a potent probiotic. Jini recommends Natren, and I personally use Natren as well.
I hope this provides some guidance, however, check with your doctor as some bacterial strains can be resistant to certain anti-pathogens. Best to you. 🙂
So, I didn’t realize that this should not be taken long-term and have been using it for several years for what started out as a remedy for someone that had previously had c-diff and lots of anitbiotics. There is the age-93-factor and also the use of 5 mg, which isn’t alot, of prednisone. I have been reseraching all this on other sites as well, and have promptly quit giving it to my relative. Maybe quitting abruptly isn’t good either? They also take Culturelle as well. Not sure what to think, and how would you know if someone has Fungemia from using this in their blood?
Hi there – this sounds like a complicated puzzle that is best addressed with your doctor or naturopath. 🙂 However, I do have some resources for you to choose another potent probiotic for you and your relative: https://blog.listentoyourgut.com/probiotic-cheat-sheet/
And here is another fantastic blog post with TONS more info on probiotics: https://blog.listentoyourgut.com/i-want-to-take-probiotics-where-do-i-start/
And one last thing – a free download, Jini’s eBook What You Need to Know About Probiotics: https://listentoyourgut.com/probiotics/
I think you will find all this info helpful in choosing the best probiotic for yourself and your relative!
Best,
– Linsy
Also, is there something else that would be recommended to help offset any issues Saccharomyces may have caused?
Hello! I think you will enjoy this video that can provide more information for you: https://blog.listentoyourgut.com/saccharomyces-boulardii-colostrum-natren-probiotics/
P.S. There are some protocol suggestions in there too! 🙂
– Linsy
Thank you for the reply. Yeah, there is alot to learn about so much of this.
Kat