One of my videos on YouTube shows people how to make their own suppositories. As you may know, we sell the kits to make your own suppositories for healing internal hemorrhoids, so I also made this video to give people an easy-to-follow tutorial. However, one of the viewers on my channel asked whether she could put Valium in the suppositories to relax rectal spasm.

I had never thought about that, although I do have an eBook on Natural Treatments for Rectal Spasm, so her question set my brain humming…

And I started thinking about what substances could be put into a suppository to relax the rectum (muscle tissue), which then led to me thinking about proctitis or localized inflammation…

I have extremely effective suppositories for anal or rectal fissures – FissureHeal – but they are not muscle relaxants, nor do they specifically target inflammation. But you know what does?

Cannabis!

Keep in mind that Cannabis sativa contains over 421 different chemical compounds, including 60 cannabinoids. But for the purpose of this article, we’ll just talk about the two most commonly studied components: THC and CBD.

So then I wondered, how does Cannabis sativa behave when administered rectally? Well there’s been a ton of research done on this powerful herb – which the medical literature refers to as a drug and of course Big Pharma is testing synthetic versions they can patent – and I found a nice overview on PubMed comparing all the different application and absorption rates of inhaled, oral, rectal, transdermal, intravenous, etc. And guess what?

Rectal absorption and utilization of cannabis is twice as effective as oral:

“Rectal administration of 2.5−5 mg of THC produced maximum plasma concentrations of 1.1−4.1 ng/ml within 2−8 h. The bioavailability of the rectal route was approximately twice that of the oral route due to higher absorption and lower first-pass metabolism.”

However, since THC is also responsible for a lot of the mental/emotional and undesirable cognitive effects of marijuana, you may want to use CBD instead. The good news is that CBD is also anti-spasmodic and anti-inflammatory:

“Cannabidiol (CBD) is a natural, non-psychoactive constituent of Cannabis sativa, but possesses pharmacological activity, which is explored for therapeutic applications. CBD has been reported to be neuroprotective, analgesic, sedating, anti-emetic, anti-spasmodic, and anti-inflammatory. In addition, it has been reported that CBD blocks anxiety produced by THC, and may be useful in the treatment of autoimmune diseases. CBD also has been reported to decrease some of the side effects of THC. These potential therapeutic applications alone warrant investigation of CBD pharmacokinetics. Further, the controversy over whether CBD alters the pharmacokinetics of THC in a clinically significant manner needs to be resolved.”

Step-by-Step Instructions

Unfortunately I cannot guide you in which brand of CBD to use, nor how much to put in each suppository. But I did find a really good article on How To Make Cannabis Suppositories you can use as a guide. I like this article because it gives you detailed instructions for 3 different strengths/dosages.

I also found this rectal cannabis suppository product you can purchase and each suppository contains 50 g of CBD oil – it doesn’t tell you the strength/concentration of CBD oil used, but at least it gives you a number to start experimenting with – or just buy it from them! They also give you a very useful tip regarding how far to insert the suppository to get maximum absorption:

“But don’t get carried away and push it too far in because if the suppository gets as high as the superior rectal vein, a proportion of the CBD will be metabolised by the liver and lost, whereas if it is absorbed by the lower two – the inferior and middle rectal vein – they don’t pass through the liver and maximum CBD is absorbed.”

So basically, you only push the suppository in about 2.5-4 cm – just past the first anal sphincter muscle.

What I can help you out with is organic cocoa butter to use as your suppository base and my video that shows you how to make even super-thin suppositories in case your anus/rectum is constricted or wounded:

TIP: If you suffer from strong menstrual cramps, these same suppositories can be inserted in the vagina – push them high up against the cervix and the same anti-spasmodic effect will relax the muscles of the uterus. HOWEVER, if using vaginally, then I would use coconut oil as the base (place in the fridge to harden), rather than cocoa butter. Coconut oil is anti-fungal and absorbs quickly. Cocoa butter would be a bit too moisturizing for vaginal tissue (I would think) and thus may lead to itchiness.

Cannabis For Crohn’s?

For those of you who are interested in using cannabis to treat your Crohn’s symptoms, this is one of the best articles I’ve read on the topic. Sorry I can’t give you any ideas/advice as I personally am not drawn to this therapy – and while I was healing myself it was not available anyway! But this article is a good place to start.

Cannabis Suppositories for Rectal Inflammation and Spasm
14 Comments

14 thoughts on “Cannabis Suppositories for Rectal Inflammation and Spasm

  • Hi Jini:
    I started drinking your shakes many years ago when you were pregnant with your youngest. I live in Vancouver and actually spoke to your mom and you on the phone a long time ago. I have spoken to Iain as well several years ago.
    I had surgery for Chron’s about 18 years ago and unfortunately I hadn’t discovered your shakes until after that. However, I did drink your shakes over all these years when I went through various flare ups etc. I went through at least a 2 or 3 year flare up several years ago and only drank your shakes as well as some of the supplements you offer. As did my friend who also has Crohn’s.
    I have been in remission for a few years and I am writing today because I have just read your article on the cannabis suppositories.
    I was thrilled that you wrote this. I can tell you and anyone who wants to know that I started taking cannabis oil when I was in the last year of that 2 or 3 year flare up. I took it from a syringe and put a bit on a cracker and took it by mouth. However, it did give the psychoactive effect which I didn’t like. Eventually, I discovered the cannabis oil in different dosages by capsule form. I have a person that I buy it from who grows it organically and lives not far from Vancouver, where I live. I am convinced that between your shakes and the cannabis capsules, it put me into remission within a few months and without the psychoactive effects. I can’t say enough to support this. If you need any more information or anyone else wants to know anything that I can help share….feel free to contact me.
    Thank you for all you give!
    Yvonne

  • I actually suffer from rectal spasms and the doctor of course gave me nothing that helped. But did I miss where to get the CBD to use in suppositories? This stuff is illegal as far as I know.

    1. Hello Cheryl,

      CBD is now legal to purchase in all US states without a prescription. It is from hemp plant and does not contain the high amounts of THC that Marijuana does. Several local and online health stores are now carrying it, so you could either research online or call your local stores to see if they are carrying it. Please let us know if we can help with anything else.

      Kind Regards,
      Rachel
      Customer Care

  • Hi Yvonne – yes I remember you and SO glad you’ve found a combination that is so effective for you! There is actually a LOT of data/trials now available on using Cannabis for all kinds of illnesses, including Crohn’s. And yes, if you can use only CBD that is definitely preferable to get the bodily benefits without the mental effects.

    Thanks for your generous offer of support to others and if anyone wants to reach you, they can either post here, or contact us and we can pass on your email. 🙂

  • I had been suffering for nearly a year with anal fissures. First I was misdiagnosed by 2 doctors and finally, when I got to the surgeon, I had a surgery as well as put myself on a radical diet. At first after the surgery, I was not healing. I started doing more research and came across Listen to Your Gut, I was hopeful. I am an herbalist and decided to make them myself at home. Much to my surprise, when I could not find a ‘recipe’ with amounts, I messaged through fb and got a response immediately on ingredient amounts. I also work with Cannabis medicine and have access to lots of different kinds. I decided to add some grass fed cannabis butter that I had made to the suppository recipe. I had another surgery scheduled, and today, 3 weeks later, I cancelled it. I attribute the bulk of my healing, expedited, from these suppositories. I have not done the research yet, but it makes sense from what I do know that the CBD would have a similar effect on smooth muscle spasms as it would other epilepsy. I can’t believe I am not in pain 10 hours a day from spasms. Truly amazing. Thank you so much for sharing your healing knowledge. You are an angel.

    1. How are you doing now after the first surgery and the suppositories? Do you feel that you have completely healed? I have the same fissure/spasm and have been trying to avoid surgery for over one year. Trying everything under the sun to heal naturally. I have not yet tried the cdb suppositories but I will.

      Thanks for your input! Robyn

  • Hi Jini:)

    My name is jonas, im from denmark, and i just purchased your book, and it all sounds very interesting. I have proctitis, and i do you think that the suppositories from endoca.com will help with the infection/ inflammation? Also if you have any other guidelines that isnt in your book, LTYG, i would really appreciate it:)

    Much love, jonas

    1. Hi Jonas,

      Jini has not personally used those suppositories nor can we comment on their efficacy with respect to your condition as we are not medical professionals and unqualified to do so but we’d love to hear your feedback if you decide to try them out. Also, make sure to check out Jini’s symptom page about proctitis if you haven’t already:

      http://www.listentoyourgut.com/symptoms/25/proctitis-or-rectal-infection.html

      Kind regards,
      Justin
      Customer Care

      1. Ok:) thank you for the answer justin!
        I have checked it out, and i am doing the stuff that she recommends:)
        A problem is that after i started on the diet(s), its like im experiencing more gas and/ or bloating than usual, and my stool is also more liquidy and infrequent than usual. Is that normal when you change your diet that radically?

        Jonas

        1. Hi Jonas,

          It’s common for bowel movements to change as the body acclimates to a different diet and gas/bloating is also common as a result of a die off effect, especially if you’re using wild oregano oil and probiotics. Usually these things normalize after 1-2 weeks. We wish you all the best and look forward to hearing how it works out for you!

          Kind regards,
          Justin
          Customer Care

  • Hi, Jini!

    So, as you probably remember, I’ve been following your Rectal StrictureHeal for some time now (a very short, but long-standing ring of scar tissue, while not severe, has taken awhile to get rid of), and while it appears to have worked like a charm (I’ve felt up in there myself, and all I feel is smooth, healthy tissue), I still have trouble with painful rectal spasming. Meditation for 20 to 30 minutes a day, as well as your Guided Meditations and self body work, have been extremely helpful, but I’m wondering now, after reading this post, if CBD is the puzzle piece that’s been missing. I’d be willing to try this, so thank you for sharing! I’ll be researching local and online stores for CBD oil this weekend.

    Stay awesome,

    Brittanee

    1. Hello Brittanee,

      That is great to hear the Rectal StrictureHeal has helped you heal your scar tissue. We would love to hear how the CBD works out for you after trying it for the rectal spasms. Continue the great work and we hope your healing continues to go great.

      Kind Regards,
      Rachel
      Customer Care

  • I just wan to say….Thank You for this invaluable, very informative, very helpful web site! I had not been able to find any alternatives to surgery until I came upon this . I have partial rectal prolapse. I had previous surgery in 2011 for total relapse, which did not succeed (I learned a couple years later.) As a result, I have suffered intensely, with chronic constipation, excruciating pain and pressure due to anal stenosis/strictures- I just learned about through this site, unpredictable bowel movements, along with incontinence (both bladder & poo,) unbearable inflammation and swelling, and extremely raw and irritated rectum. I also have rectal spasms, which I have no control over and was forced to terminate employment last fall because of all these impossible symptoms. As a result, I have taken early retirement which barely supplements my husband’s monthly disability check. I have missed out on so much life with family, friends, and just being able to function normally as a person. Please bear with me, I know I am vomiting all over you, but you are the first place I have found that really understands; it’s not like you can talk about this with just anybody; this has been going on so long, I feel like it defines me. Thank you for listening, and again…thank you for this answer to my prayers…God Bless You!

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